Best-in-Class Quality Controls and Reference Materials for Liquid Biopsy Assays
NIPT Trisomy 13, 18 & 21 Controls
cfDNA contains Trisomy 13, 18 and 21 gDNA mixed with female gDNA at 2.5%, 5%, 7.5%, and 10% spiked in DNA-depleted human plasma. Used for counting-based assay, such as PerkinElmer’s Vanadis®.
cfDNA Standards For Molecular Testing
Multiplexed ctDNA fragments (~150bp) mixed with nucleosomally fragmented wildtype cfDNA background in human plasma. The cell-derived ctDNA fragments are generated by Anchor’s unique multiplexed gene-editing method and are nucleosomally fragmented to around 150bp. The cell-derived variants are suitable for both the amplicon-based and capture-based methods. The synthetic ctDNA fragments are gBlocks-like dsDNA of 150-170bp and are suitable for amplicon-based applications, including ddPCR, qPCR, and amplicon-based NGS.
DNA-Depleted Plasma
Build your own controls using your high-positive samples to save time. With our DNA-depleted human plasma (DNA-free plasma) as a matrix, you can produce reference materials specific to your time-sensitive needs while retaining the natural components of the sample.
Prefer to have a knowledgeable lab do the work? Send your plasma to Anchor Molecular and we’ll remove the DNA background for you.
Two Grades:
Regular Grade: residue gDNA at 0-20 pg/ml
Economy Grade: residue gDNA at 20-100 pg/ml
AM Normal Cell Free gDNA
AM Normal cfgDNA-1
Description: DNA is extracted and fragmented from a popular normal male cell line
Dissolved in TE: Part Number: 60133001
10ug per vial
Spiked in Plasma: Part Number: 60133501
Pre-spiked with 250ng gDNA per 5ml
AM Variant Cell Free gDNA
AM Multiplexed ctDNA
Description: DNA contains multiplexed 20+ cell-derived variants each at 5% Allele Frequency. DNA is extracted and fragmented from mutated PAM3005 cells
Dissolved in TE: Part Number: 60135001
10ug per vial
Spiked in Plasma: Part Number: 60135501
Pre-spiked with 250ng gDNA per 5ml
Mass Spec Zero
AM Mass Spec Zero 1000. Human plasma is negative for hormones, steroids, and bile acids.
AM Mass Spec Zero 2000. Human plasma is negative for hormones, steroids, bile acids, and vitamins.
COVID19/Influenza/RSV Quality Control and Standards
The Anchor COVID19/Influenza/RSV Quality Controls are intended for use by clinical labs and assay manufacturers to assess the performance of any molecular-based testing of SARS-COV-2, Influenza A and B, Respiratory Syncytial Virus (RSV) A and B.
PRODUCT DESCRIPTION:
The Control and Reference Standards contain a non-pathogenic recombinant RNA virus carrying full-length of SARS-COV-2, complete segments 7 and 8 of Influenza A and B (targets of nearly all assays), and the most conserved regions on RSV A & B. They are accurately quantified traceable to physically quantified DNA standards. Stable. Easy to use. Customized titers are available. Please contact us for detailed information.
Read More “COVID19/Influenza/RSV Quality Control and Standards”
Anchor SARS-COV-2 Quality Control
Anchor SARS-COV-2 Quality Control
Part Number: 60230001
6 Vials, 2 mL Fill Volume, -20°C Storage
Product Insert
Safety Data Sheet
LIMITATIONS:
For Research Use Only. Not for use in diagnostic procedures.
Anchor SARS-COV-2 Reference Panel
Anchor SARS-COV-2 Reference Panel
Part Number: 60230002
4 Vials of positives and 1 vial of negative
(0, 1000, 10,000, 100,000 and 1,000,000 copies/ml,
Negative has 10,000 copy/ml human gDNA),
1 mL Fill Volume, -20°C Storage
cfDNA Extraction Sensitivity Controls
Does your cfDNA extraction process affect the Limit of Detection (LOD) of a particular gene target? Our new products, cfDNA Extraction Sensitivity Panels and Extraction Low Positive Controls, can help your research and development for liquid biopsy assays.
cfDNA Extraction Specificity Controls
The Plasma Genomic cfDNA Extraction Control is for the purpose of monitoring the degree of genomic DNA (gDNA) contamination in the extracted cfDNA. DNA-free plasma is spiked with either with high molecular weight gDNA molecules or 170 bp cfDNA fragments or both.