Twenty-three Multiplexed nucleosomally fragmented ctDNA fragments (~150bp) mixed with normal patient cfDNA background in human plasma. The cell-derived ctDNA fragments are generated by Anchor’s unique multiplexed gene-editing method and are nucleosomally fragmented to around 150bp. The cell-derived variants are suitable for capture-based methods.
For customer SNV/indel/fusion variants for either cfDNA assays or solid tumor tests, please request by clicking the “Order Here” button and select the “Customer Molecular Controls” option.
The Allele Frequency of the variants below were determined by ddPCR
| Cell Derived Variant | |||
|---|---|---|---|
| APC Q1429* | EGFR E746-A750del v1&v2 | KIT D816V | PIK3CA E545K |
| APC R1450* | EGFR L858R | KRAS G12C | PIK3CA H1047R |
| BRAF V600E | EGFR T790M | KRAS G12D | PTEN R130G |
| CTNNB1 T41A | FGFR3 S249C | KRAS G12V | TP53 R175H |
| EGFR C797S | IDH1 R132H | NRAS Q61R | TP53 R248Q |
| EGFR D770_N771insG | BRCA1 P871L | BRCA2 N372H | |
| Cat. No. | Base Matrix | Allele Frequency (%) | Total gDNA(ng) |
|---|---|---|---|
| 60100103 | Buffer (15ul) | 3% | 300 |
| 60100104 | EDTA Plasma (5ml) | 3% | 125 |
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