Custom DNA RNA mutations for NGS or PCR-based Testing

Custom DNA RNA Mutations for NGS or PCR-based Testing

DNA_RNA_Mutation

The ctDNA fragments are around 150bp, carrying mutations at random locations on the fragments. The Allele Frequencies can be from 0.02% to 5%, determined by ddPCR. The wildtype cfDNA is either from normal cell line or normal patient cells. The cfDNA profile is below: