DNA-depleted human plasma is essential in various scenarios where the presence of background DNA could interfere with the accuracy and reliability of results. Here are some key applications:
Cell-Free DNA (cfDNA) Analysis: Ideal for liquid biopsy research in cancer diagnostics and monitoring, DNA-depleted plasma ensures that only cfDNA is detected, significantly improving assay accuracy.
Assay Development and Validation: Ideal matrix for liquid biopsy assay development in cancer diagnostics and monitoring, DNA-depleted plasma ensures that cfDNA is detected with authentic accuracy, precision and assay linearity in complicated human plasma environment.
Pathogen DNA Detection: Crucial for detecting true copies of viral or bacterial DNA in plasma matrix, DNA-depleted plasma reduces the risk of false positives caused by background contaminating DNA from unknown . Crucial for detecting true copies of viral or bacterial DNA in plasma matrix, DNA-depleted plasma reduces the risk of false positives caused by background contaminating DNA from unknown .
Quality Control: Used to create reference materials that mimic patient samples without the variability introduced by background DNA, ensuring consistent and reliable performance of diagnostic tests.
Research on Host-Pathogen Interactions: Facilitates studies focusing on the interactions between host and pathogen DNA by clearly distinguishing between the two, leading to more precise research outcomes.
Using DNA-depleted plasma in these scenarios enhances the specificity, sensitivity, and overall reliability of molecular testing and research.
Immuno-Non-reactive Serumis immunologically non-reactive to various antigens. It is a negative matrix suitable for various immunological applications where the presence of antigens could interfere with experimental outcomes.
HBV Negative Serum is immunologically non-reactive to both HBV antigens and antibodies. It's a negative matrix suitable for diagnostic applications where the presence of HBV antigens or antibody could interfere with the results.
Storage Condition: 2-8°C for short term (3-12 months), -20ºC for long term (> 1 year)
Shipping Condition: Blue Ice.
Shelf Life: Five years from the date of receipt under proper storage condition.
RNA-Depleted Plasma is made from pooled human plasma with its RNA content removed. It can be used as a real patient-like matrix for applications such as cell-free RNA assays.