DNA-Depleted Plasma

DNA-Depleted Plasma

Build your own controls using your high-positive samples to save time. With our DNA-depleted human plasma (DNA-free plasma) as a matrix, you can produce reference materials specific to your time-sensitive needs while retaining the natural components of the sample.

Prefer to have a knowledgeable lab do the work? Send your plasma to Anchor Molecular and we’ll remove the DNA background for you.

Two Grades:
Regular Grade: residue gDNA at 0-20 pg/ml
Economy Grade: residue gDNA at 20-100 pg/ml





Regular Grade:

Product Name Cat. No. Size (ml)
DD Plasma (DNA-Depleted Plasma) 60601001 1000
DD Plasma (DNA-Depleted Plasma) 60601002 500
DD Plasma (DNA-Depleted Plasma) 60601003 100
DD Plasma (DNA-Depleted Plasma) 60601004 50

Economy Grade:

Product Name Cat. No. Size (ml)
DD Plasma (DNA-Depleted Plasma) 60601011 1000
DD Plasma (DNA-Depleted Plasma) 60601012 500
DD Plasma (DNA-Depleted Plasma) 60601013 100
DD Plasma (DNA-Depleted Plasma) 60601014 50

Why Use DNA-Depleted EDTA Plasma?

Characterization of DNA-Depleted Plasma

  • Highest quality DNA-depleted human plasma
  • For use in research, assay development, & daily assays
  • Retains naturally-occurring, interfering proteins
  • Allows for more realistic process in quality systems
  • Customized plasma available upon request
  • Price upon request
  • Less processed plasma (more DNA: 20-100 pg/ml or higher) is available upon request

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Concentration of Human gDNA:  < 20 pg/mL
Total protein: 5-7 g/dL
Immunoglobulin G: 500-1700 mg/dL
Immunoglobulin A: 90-400 mg/dL
Immunoglobulin M: 20-172 mg/dL
Cholesterol, Total:  50-199 mg/dL
Triglycerides: 50-149 mg/dL
HDL Cholesterol:  > 20 mg/dL
VLDL Cholesterol: 10-40 mg/dL
LDL Cholesterol:  20-99 mg/dL
pH: 7.2-7.6
Tested Negative for HIV, HBV, HCV,
 HTLV and Syphilis by FDA approved methods

Exosome counts in DNA-depleted plasma are normal compared to regular plasma.

Why Is Plasma Better Than Buffer As Reference Material Matrix?

A plasma matrix is a better representation of a real patient sample because the natural, interfering proteins are retained. This allows for a more realistic process in your quality system.

Equal amounts of DNA fragments were spiked into TE Buffer (blue) and human plasma (red).

While the 170 bp peak was recovered similarly in each matrix, much more genomic DNA was extracted from the plasma than from the TE buffer resulting in a more patient-like matrix.
See Figure A.